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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP49
All Species:
13.64
Human Site:
Y543
Identified Species:
30
UniProt:
Q70CQ1
Number Species:
10
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70CQ1
NP_061031.2
688
79198
Y543
A
R
K
Q
L
M
I
Y
R
L
P
Q
V
L
R
Chimpanzee
Pan troglodytes
XP_518467
759
87316
Y614
A
R
K
Q
L
M
I
Y
R
L
P
Q
V
L
R
Rhesus Macaque
Macaca mulatta
XP_001085246
657
75261
E510
F
T
E
T
E
A
L
E
G
R
I
Y
A
C
D
Dog
Lupus familis
XP_532134
681
77708
Y536
A
R
K
Q
L
M
I
Y
R
L
P
Q
V
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9L4
685
78254
Y540
A
R
K
Q
L
M
I
Y
R
L
P
Q
V
L
R
Rat
Rattus norvegicus
B2GUX4
565
62681
E426
C
F
S
L
F
T
K
E
E
E
L
E
S
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510004
1411
160789
L565
K
Q
L
M
V
C
R
L
P
Q
V
L
R
L
H
Chicken
Gallus gallus
O57429
357
40913
D218
L
R
L
F
T
K
E
D
V
L
D
G
D
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392160
541
61414
F402
L
A
D
S
E
L
Y
F
C
D
N
C
M
G
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792596
510
58338
D371
G
G
L
N
G
G
S
D
D
T
T
V
D
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
F332
K
K
E
Q
L
K
D
F
N
Y
H
C
G
E
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
90.6
92.1
N.A.
90.4
22.9
N.A.
31.1
20.9
N.A.
N.A.
N.A.
N.A.
31.3
N.A.
25.5
Protein Similarity:
100
90.5
92
93.9
N.A.
94.1
38
N.A.
38.5
32.4
N.A.
N.A.
N.A.
N.A.
45.3
N.A.
40.1
P-Site Identity:
100
100
0
100
N.A.
100
0
N.A.
6.6
13.3
N.A.
N.A.
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
13.3
100
N.A.
100
6.6
N.A.
20
20
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
10
0
0
0
10
0
0
0
0
0
0
10
0
0
% A
% Cys:
10
0
0
0
0
10
0
0
10
0
0
19
0
10
10
% C
% Asp:
0
0
10
0
0
0
10
19
10
10
10
0
19
0
10
% D
% Glu:
0
0
19
0
19
0
10
19
10
10
0
10
0
28
0
% E
% Phe:
10
10
0
10
10
0
0
19
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
10
10
0
0
10
0
0
10
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
37
0
0
0
10
0
0
0
0
% I
% Lys:
19
10
37
0
0
19
10
0
0
0
0
0
0
0
19
% K
% Leu:
19
0
28
10
46
10
10
10
0
46
10
10
0
46
0
% L
% Met:
0
0
0
10
0
37
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
10
0
10
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
37
0
0
10
0
% P
% Gln:
0
10
0
46
0
0
0
0
0
10
0
37
0
0
0
% Q
% Arg:
0
46
0
0
0
0
10
0
37
10
0
0
10
0
37
% R
% Ser:
0
0
10
10
0
0
10
0
0
0
0
0
10
0
10
% S
% Thr:
0
10
0
10
10
10
0
0
0
10
10
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
10
0
10
10
37
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
37
0
10
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _